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synergy k broad spectrum vitamin k1 and vitamin k2 complex now with 1 000 iu vitamin d3 for bone and arterial health supports bone and blood vessel health promote bone mineralization made with hypoallergenic vegetarian ingredients synergy k is a blend of vitamin k1 k2 and d3 to help promotes healthy calcium utilization in order to maintain healthy bones and blood vessel function synergy k specifically helps support bone formation as well as healthy calcium metabolism in vascular tissue to support vascular elasticity vitamin k includes a group of compounds that contain a central ring structure with varying side chains these differing side chains account for variations in absorption bioavailability transport and tissue distribution vitamin k1 phylloquinone is the most common form and is found in plants and green vegetables the vitamin k2 family menaquinones are less common and are found in meats eggs some cheeses and fermented food such as japanese natto the most common menaquinones are menaquinone 4 mk 4 and menaquinone 7 mk 7 studies indicate that vitamin k1 and mk 4 are primarily concentrated in the liver while mk 7 concentrates in extra hepatic tissues including vascular tissues and has a longer half life vitamin k enhances bone formation by carboxylating osteocalcin this enables osteocalcin to bind to calcium and promote healthy bone mineralization adequate intake of vitamin k1 and k2 may be especially important for optimal carboxylation in aging individuals as indicated by a recent study involving japanese women by activating matrix gla protein mgp vitamin k also helps maintain healthy calcium metabolism in vascular tissues supporting healthy vascular elasticity recent studies indicate that vitamin d also potentiates the activity of mgp and that the combination of vitamin k and d provides synergistic support for blood vessel function and bone health vitamin k supplementation is contraindicated for those taking coumadin warfarin anticoagulant medication